This study is no longer recruiting.
Do you feel limited by Eosinophilic Esophagitis (EoE)?
If you have EoE or symptoms of EoE, you may be eligible to participate in the VOYAGE study which may provide relief from EoE pain and discomfort
Do you feel limited by Eosinophilic Esophagitis (EoE)?
If you have EoE or symptoms of EoE, you may be eligible to participate in the VOYAGE study which may provide relief from EoE symptoms.

Can I participate?

You may be able to participate in the VOYAGE clinical trial if you:

Are between the ages of 18–65

Have active
eosinophilic esophagitis (EoE)

Have had difficulty swallowing (dysphagia) at least twice a week for 2 weeks

Other eligibility criteria applies.
If you do not have a confirmed EoE diagnosis but are in the process of speaking with your doctor, you can apply once you have an official diagnosis.
In the VOYAGE study you will be seen by EoE doctors, help advance EoE research, and you may receive an investigational drug that may provide relief to your symptoms.

What you may receive

Study related treatment at no cost
Medical treatment related to EoE
Travel, lodging and meal reimbursements for clinic visits

Why should I participate?

We are looking for participants to take part in important research, intended to improve EoE symptoms and treatment.
By enrolling in this Phase 2 trial
You could potentially see relief to your symptoms in the following ways:
Reduced pain and inflammation  
Ease of difficulty and pain when swallowing    
Reduced chances of choking
You will be seen by EoE specialists and your participation in this study will help lead to a better understanding of the investigational drug, etrasimod.

What’s the purpose of this clinical trial?

The purpose of this study is to evaluate how the investigational drug, etrasimod, helps patients fight EoE symptoms.

What’s involved?


How do I get started?
Click HERE and enter your information to express interest in the study.  
Where is the study conducted?
The study will be conducted in various locations in the United States, Europe and Australia.
How will the investigational drug be taken?
The drug will be taken orally (by mouth) once per day.
What side effects should I expect?  
Common side effects are headache, dizziness, mouth ulcers, skin rash caused by direct contact of the skin with a substance, constipation, diarrhea, and a reduction in white blood cell counts.
Has the investigational drug been tested before?
The investigational drug has been studied in other inflammatory diseases, including ulcerative colitis and abnormal liver function.
Is there any cost for me to participate?
There is no cost to you or your insurance provider for participating in the trial. If you qualify for the trial, you may be reimbursed for your travel expenses.
Can I leave the study at any time?
You’re free to withdraw from the study at any time. If and when you sign up, your participation is completely voluntary.
How long will the study take place?
The study will last up to 60 weeks.
If pre-qualified, what can I expect on my first visit to the study center?
You will undergo tests and assessments, answer questionnaires, and record instances of difficulty in swallowing in an eDiary [electronic diary] to determine if you are eligible to take part in this study.
What is the importance of clinical studies for EoE?
The aim of current treatments is to reduce pain and inflammation. The available treatments may improve symptoms for some people, but they may have unacceptable side effects, be difficult to stick to, or not work well for others. Therefore, there is a need to develop and find new treatments for people with EoE through clinical studies.
Do I need health insurance?
No, health insurance is not needed in order to participate.

Stay updated.

Study news, announcements and more.
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